Human Sialic Acid Binding Ig Like Lectin 8 (SIGLEC8) ELISA Kit
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935106861
info@markelab.com
Precio
662.5€ (96 tests)
Elisa Kits SIGLEC8
proveedor
Abbexareference
abx153088Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Sialic Acid Binding Ig Like Lectin 8 (SIGLEC8) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Sialic Acid Binding Ig Like Lectin 8 (SIGLEC8) concentrations in cell lysates. This assay has high sensitivity and excellent specificity for detection of Sialic Acid Binding Ig Like Lectin 8 (SIGLEC8)No significant cross-reactivity or interference between Sialic Acid Binding Ig Like Lectin 8 (SIGLEC8) and analogues was observed.
Background
SIGLEC8 is an inhibitory receptor expressed mainly on eosinophils, mast cells, and basophils. It binds selectively to 6′-sulfated sialyl Lewis X and related glycan ligands, regulating inflammatory responses in allergic diseases. Activation of SIGLEC8 leads to eosinophil apoptosis and inhibition of mast cell degranulation, making it an attractive therapeutic target for asthma and eosinophilic disorders. Its function is mediated through ITIMs, which dampen cell activation pathways. SIGLEC8 is also implicated in maintaining immune homeostasis in tissues and resolving allergic inflammation.
Características del producto
category
ELISA Kits
immunogen target
Sialic Acid Binding Ig Like Lectin 8 (SIGLEC8)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.06 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Cell lysates
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
SAF2,SIGLEC-8,SIGLEC8L,Sialoadhesin family member 2
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
SIGLEC8
dry ice
No
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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