Human SH2 domain-containing protein 6 (SH2D6) ELISA Kit
715€ (96 tests)
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935106861
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name
Human SH2 domain-containing protein 6 (SH2D6) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx545654
tested applications
ELISA
Description
Human SH2 domain-containing protein 6 (SH2D6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human SH2 domain-containing protein 6 (SH2D6) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | SH2 domain-containing protein 6 (SH2D6) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q7Z4S9 |
| Alias | SH2D6 |
| Background | Elisa kits for SH2D6 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
SH2D6 is an adaptor protein containing an SH2 domain, functioning as a mediator of signal transduction pathways downstream of activated cytokine and growth factor receptors. It participates in pathways such as JAK/STAT and MAPK, facilitating signal relay to regulate cell proliferation, differentiation, and survival. SH2D6 is expressed predominantly in hematopoietic and immune cells, where it plays roles in cytokine signaling, lymphocyte development, and immune cell activation. It interacts with signaling proteins via its SH2 domain, bridging upstream receptors to downstream effectors during immune responses. Dysregulation of SH2D6 has been linked to immune dysfunction and inflammatory disorders due to impaired cytokine signaling regulation. Knockout models show defects in lymphocyte activation, reduced cytokine production, and abnormal immune responses, emphasizing its importance in maintaining immune signaling and homeostasis.
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