Human SERPINB3 (Serpin B3) ELISA Kit

Este producto es parte de SERPINB3 - serpin family B member 3
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935106861
info@markelab.com
name
Human SERPINB3 (Serpin B3) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH1536
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Human
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
78.125-5000pg/ml
Sensitivity
46.875pg/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
P29508
Alias
SCC,T4-A,SCCA1,SSCA1,SCCA-1,HsT1196,SCCA-PD,Serpin B3,Protein T4-A,Squamous cell carcinoma antigen 1
Background
Elisa kits for SERPINB3
Status
RUO

SERPINB3, also known as squamous cell carcinoma antigen 1 (SCCA1), is a member of the serine protease inhibitor (SERPIN) superfamily. This family of proteins plays critical roles in regulating various physiological processes, including inflammation, apoptosis, and immune responses. SERPINB3 was first identified due to its overexpression in squamous cell carcinomas, a type of skin cancer, which has made it a significant biomarker in oncology. The SERPINB3 gene is located on chromosome 18q21, where it resides in a cluster with several other SERPIN genes, including SERPINB4, with which it shares a high degree of homology. SERPINB3 is primarily expressed in epithelial tissues, particularly in the skin and mucous membranes. It is upregulated in response to various stressors, such as inflammation, hypoxia, and oxidative stress, indicating its role in cellular defense mechanisms.

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