Human SERPINA3 (Alpha-1-antichymotrypsin) QuickTest ELISA Kit
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Product specifications
| Category | ELISA Kits |
| Reactivity | Human |
| Assay Data | 120 minutes |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 1.563-100nmol/ml |
| Sensitivity | 0.938nmol/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, cell culture supernatant, cell lysate or tissue lysate, other biological fluid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P01011 |
| Alias | ACT,AACT,GIG24,GIG25,Alpha-1-antichymotrypsin,Cell growth-inhibiting gene 24/25 protein,Serpin A3 |
| Background | Elisa kits for SERPINA3 |
| Status | RUO |
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Human SERPINA3 (Alpha-1-antichymotrypsin) ELISA Kit
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SERPINA3 antibody
The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
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Human SerpinA3, also known as Alpha 1-antichymotrypsin(AACT), is a member of the serine protease inhibitor class, and is a plasma alpha globulin glycoprotein which increases in the blood during the inflammatory process. SerpinA3, is also an inhibitor of neutrophil cathepsin G, mast cell chymases and pancreatic chymotrypsin. SerpinA3 is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease. SerpinA3 has also been implicated in the pathology of a number of devastating human diseases including chronic obstructive pulmonary disease(COPD), Parkinson’s disease(PD), Alzheimer’s disease(AD), Stroke, Cystic Fibrosis, Cerebral Haemorrhage and Multiple System Atrophy.
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