Human Serpin I2 (SERPINI2) Protein
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Description
Human Serpin I2 Protein is a recombinant protein from Human produced in Human Cells. Recombinant Human Serine Protease Inhibitor-clade I2 is produced by our Mammalian expression system and the target gene encoding Ser19-Leu405 is expressed with a 6His tag at the C-terminus.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Serpin I2 |
| Host | Human |
| Origin | Human |
| Observed MW | Molecular Weight: 45.1 kDa Sequence Fragment: Ser19-Leu405 Tag: C-terminal 6 His tag |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | 20mM PB, 150mM NaCl, pH7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store at < -20°C. |
| Dry Ice | No |
| UniProt ID | O75830 |
| Alias | MEPI,PI14,PANCPIN,TSA2004,Serpin I2,Myoepithelium-derived serine protease inhibitor,Pancpin,Peptidase inhibitor 14 |
| Background | Protein SERPINI2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
SERPINI2 is a member of the serine protease inhibitor (serpin) family and is encoded by the SERPINI2 gene located on chromosome 3. The serpin superfamily comprises a large group of proteins that inhibit proteolytic enzymes, playing crucial roles in various biological processes such as blood coagulation, fibrinolysis, immune response, and tissue remodeling. Like other serpins, SERPINI2 regulates the activity of proteases by acting as a suicide substrate, forming a stable complex with the target protease, which leads to its irreversible inhibition. Although SERPINI2 is not as well-studied as other members of the serpin family, recent studies suggest that it is involved in the regulation of proteolysis in various tissues, with significant expression observed in pancreatic, hepatic, and other glandular tissues.
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