Human Serpin B3 (SERPINB3) Protein
234€ (5 µg)
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935106861
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name
Human Serpin B3 (SERPINB3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680344
tested applications
SDS-PAGE
Description
Human Serpin B3 (SERPINB3) Protein is a recombinant protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Serpin B3 (SERPINB3) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| Alias | SCC,T4-A,SCCA1,SSCA1,SCCA-1,HsT1196,SCCA-PD,Serpin B3,Protein T4-A,Squamous cell carcinoma antigen 1 |
| Background | Protein SERPINB3 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
SERPINB3, also known as squamous cell carcinoma antigen 1 (SCCA1), is a member of the serine protease inhibitor (SERPIN) superfamily. This family of proteins plays critical roles in regulating various physiological processes, including inflammation, apoptosis, and immune responses. SERPINB3 was first identified due to its overexpression in squamous cell carcinomas, a type of skin cancer, which has made it a significant biomarker in oncology. The SERPINB3 gene is located on chromosome 18q21, where it resides in a cluster with several other SERPIN genes, including SERPINB4, with which it shares a high degree of homology. SERPINB3 is primarily expressed in epithelial tissues, particularly in the skin and mucous membranes. It is upregulated in response to various stressors, such as inflammation, hypoxia, and oxidative stress, indicating its role in cellular defense mechanisms.
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