Human Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Protein
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935106861
info@markelab.com
Precio
200€ (10 µg)
Protein ACVRL1
proveedor
Abbexareference
abx652178Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) Protein is a Recombinant protein from Human.
Background
ACVRL1, also known as ALK1, is a type I receptor that primarily binds BMP9 and BMP10. It is critical for vascular development and endothelial cell function. ACVRL1 regulates angiogenesis through the SMAD1/5/8 signaling pathway, promoting endothelial proliferation and vessel stability. Mutations in ACVRL1 cause hereditary hemorrhagic telangiectasia (HHT), a genetic disorder characterized by abnormal blood vessel formation and recurrent bleeding. It is primarily expressed in vascular endothelial cells.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Serine/threonine-Protein Kinase Receptor R3 (ACVRL1)
host
E. coli
conjugation
Unconjugated
form
Lyophilized
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
expression
Recombinant
purity
> 97%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ACVRL1
dry ice
No
availability
Shipped within 5-12 working days.
alias
Activin receptor-like kinase 1,ALK-1,SKR3
uniprot id
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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