Human Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) ELISA Kit
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935106861
info@markelab.com
Precio
618.75€ (96 tests)
Elisa Kits ACVRL1
proveedor
Abbexareference
abx150614Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Serine/threonine-Protein Kinase Receptor R3 (ACVRL1) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Activin Receptor Like Kinase 1 (ALK1)No significant cross-reactivity or interference between Activin Receptor Like Kinase 1 (ALK1) and analogues was observed.
Background
ACVRL1, also known as ALK1, is a type I receptor that primarily binds BMP9 and BMP10. It is critical for vascular development and endothelial cell function. ACVRL1 regulates angiogenesis through the SMAD1/5/8 signaling pathway, promoting endothelial proliferation and vessel stability. Mutations in ACVRL1 cause hereditary hemorrhagic telangiectasia (HHT), a genetic disorder characterized by abnormal blood vessel formation and recurrent bleeding. It is primarily expressed in vascular endothelial cells.
Características del producto
category
ELISA Kits
immunogen target
Serine/threonine-Protein Kinase Receptor R3 (ACVRL1)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.06 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
Activin receptor-like kinase 1,ALK-1,SKR3
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
ACVRL1
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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