Human SATB2 (Special AT-rich sequence-binding protein 2) ELISA Kit
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Name
Human SATB2 (Special AT-rich sequence-binding protein 2) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH12080
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 31.25-2000pg/ml |
| Sensitivity | 18.75pg/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | Q9UPW6 |
| Alias | C2DELq32q33,DEL2Q32Q33,GLSS,Special AT-rich sequence-binding protein 2,DNA-binding protein SATB2 |
| Background | Elisa kits for SATB2 |
| Status | RUO |
Background
SATB homeobox 2 (SATB2) is a transcription factor that plays a crucial role in chromatin organization, gene regulation, and cellular differentiation SATB2 is involved in the regulation of skeletal development, neural differentiation, and craniofacial patterning, particularly during embryogenesis It functions by binding to specific DNA sequences and organizing chromatin into loops, facilitating the regulation of gene expression in a spatially organized manner SATB2 is highly expressed in osteoblasts and neurons, where it influences the expression of genes involved in bone formation and synaptic plasticity Mutations in SATB2 lead to developmental disorders such as SATB2-associated syndrome, which is characterized by intellectual disability, speech delays, and craniofacial abnormalities SATB2 also plays a role in cancer, where it can modulate tumor progression and metastasis through its effects on chromatin structure and gene expression Recent studies have highlighted its potential as a therapeutic target for regenerative medicine and in disorders involving disrupted bone and neural development
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