Human SATB Homeobox Protein 2 (SATB2) Protein

Este producto es parte de SATB homeobox
Human SATB Homeobox Protein 2 (SATB2) Protein
208€ (10 µg)

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Name
Human SATB Homeobox Protein 2 (SATB2) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx654990
Tested Applications
WB, SDS-PAGE

Description

Human SATB Homeobox Protein 2 (SATB2) Protein is a recombinant Human protein expressed in E. coli.

Documentos del producto

Instrucciones
Data sheet
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Especificaciones del producto

Category
Proteins and Peptides
Immunogen Target
SATB Homeobox Protein 2 (SATB2)
Host
E. coli
Assay Type
Activity: Not tested
Sequence Fragment: Lys350-His672
Tag: N-terminal His tag
Origin
Human
Conjugation
Unconjugated
Observed MW
Calculated MW: 40.6 kDa  Observed MW (SDS-PAGE): 44 kDa
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles.
Dry Ice
No
UniProt ID
Q9UPW6
Alias
C2DELq32q33,DEL2Q32Q33,GLSS,Special AT-rich sequence-binding protein 2,DNA-binding protein SATB2
Background
Protein SATB2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Concentration: Prior to lyophilization: 200 µg/ml

Background

SATB homeobox 2 (SATB2) is a transcription factor that plays a crucial role in chromatin organization, gene regulation, and cellular differentiation SATB2 is involved in the regulation of skeletal development, neural differentiation, and craniofacial patterning, particularly during embryogenesis It functions by binding to specific DNA sequences and organizing chromatin into loops, facilitating the regulation of gene expression in a spatially organized manner SATB2 is highly expressed in osteoblasts and neurons, where it influences the expression of genes involved in bone formation and synaptic plasticity Mutations in SATB2 lead to developmental disorders such as SATB2-associated syndrome, which is characterized by intellectual disability, speech delays, and craniofacial abnormalities SATB2 also plays a role in cancer, where it can modulate tumor progression and metastasis through its effects on chromatin structure and gene expression Recent studies have highlighted its potential as a therapeutic target for regenerative medicine and in disorders involving disrupted bone and neural development

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