Human S1PR3 (Sphingosine 1-phosphate receptor 3) ELISA Kit

Este producto es parte de S1PR - Sphingosine 1 Phosphate Receptor
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935106861
info@markelab.com
name
Human S1PR3 (Sphingosine 1-phosphate receptor 3) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH0849
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Human
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.156-10ng/ml
Sensitivity
0.094ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
Q99500
Alias
S1PR3,C9orf108,C9orf47,EDG-3,EDG3,LPB3,S1P3,endothelial differentiation G protein-coupled receptor 3
Background
Elisa kits for S1PR3
Status
RUO

S1PR3 is a G protein-coupled receptor for sphingosine-1-phosphate (S1P), widely expressed in endothelial cells, smooth muscle cells, and immune cells. It couples to multiple G proteins (Gq, Gi, and G12/13), activating signaling pathways such as PI3K/Akt, MAPK, and Rho/ROCK. S1PR3 regulates vascular tone, endothelial barrier integrity, and smooth muscle contraction, contributing to blood flow regulation and vascular development. It also influences immune cell migration, inflammatory responses, and cardiac function. In the cardiovascular system, S1PR3 is essential for vasodilation and cardioprotection. Dysregulation of S1PR3 has been associated with chronic inflammation, cardiovascular diseases, and cancer progression. In tumor biology, S1PR3 promotes angiogenesis, metastasis, and immune cell infiltration into the tumor microenvironment. Therapeutically, targeting S1PR3 is being explored for its potential to regulate vascular inflammation, immune responses, and cancer metastasis, making it a promising target in inflammatory and cardiovascular diseases.

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