Human Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3) Protein
208€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx654937
tested applications
WB, SDS-PAGE
Description
Human Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3) Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Please enquire. Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| Alias | RXFP3, RLN3R1,RXFPR3,GPCR135,relaxin/insulin like family peptide receptor 3,SALPR |
| Background | Protein RXFP3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
RXFP3 is a G protein-coupled receptor that is activated by relaxin-3, a member of the relaxin/insulin-like family. This receptor primarily couples to Gi proteins, leading to the inhibition of adenylate cyclase and reducing cAMP levels. RXFP3 is expressed in the central nervous system, particularly in regions such as the hypothalamus, where it plays a key role in regulating stress responses, appetite, and circadian rhythms. Activation of RXFP3 has been shown to influence feeding behavior, emotional responses, and neuroendocrine functions by modulating neurotransmitter release and neuronal excitability. Dysregulation of RXFP3 signaling is associated with disorders like anxiety, depression, and metabolic syndrome. As a therapeutic target, RXFP3 agonists could potentially be used to address stress-related conditions and appetite regulation, while antagonists may be useful in managing mood disorders and obesity.
Related Products
Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3) Antibody
RXFP3 is a receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
Ver Producto
Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3) Antibody
RXFP3 Antibody is a Rabbit Polyclonal antibody against RXFP3.
Ver Producto
Human Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3) ELISA Kit
Human Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Relaxin/Insulin Like Family Peptide Receptor 3 (RXFP3)
Ver Producto