Human Receptor-type tyrosine-protein phosphatase U (PTPRU) ELISA Kit
![Human Receptor-type tyrosine-protein phosphatase U (PTPRU) ELISA Kit](/_next/image?url=https%3A%2F%2Fwww.abbexa.com%2Fimage%2Fcache%2Fcatalog%2FGraphs%2F29%2Fabx540772%2Fabx540772_Human_Receptor-type_tyrosine-protein_phosphatase_U_PTPRU_ELISA_Kit_graph-250x250.png&w=3840&q=75)
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits PTPRU
proveedor
Abbexareference
abx540772Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Receptor-type tyrosine-protein phosphatase U (PTPRU) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Receptor-type tyrosine-protein phosphatase U (PTPRU) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
PTPRU, also known as RPTPρ, is a receptor-like protein tyrosine phosphatase that regulates cell adhesion, migration, and differentiation. It contains extracellular immunoglobulin (Ig)-like and fibronectin type III domains, a transmembrane segment, and two intracellular phosphatase domains, with the first domain being enzymatically active. PTPRU is expressed in epithelial tissues, the nervous system, and during embryonic development. It interacts with cadherins and β-catenin, mediating cell adhesion and cytoskeletal organization. PTPRU regulates Wnt/β-catenin signaling, playing a role in cellular proliferation, differentiation, and tissue development. Its expression is developmentally regulated, and dysregulation has been linked to tumor progression in various cancers, including colorectal and breast cancer. PTPRU is also implicated in stem cell maintenance and differentiation, underscoring its importance in tissue homeostasis and development. Its ability to influence cellular adhesion and signaling makes it relevant for understanding cancer and developmental biology.
Características del producto
category
ELISA Kits
immunogen target
Receptor-type tyrosine-protein phosphatase U (PTPRU)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.06 ng/ml
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
FMI,PTP,PCP-2,PTP-J,PTPRO,PTPU2,PTP-PI,PTP-RO,PTPPSI,hPTP-J,R-PTP-U,R-PTP-PSI,Protein-tyrosine phosphatase receptor omicron,Receptor-type protein-tyrosine phosphatase psi,Protein-tyrosine phosphatase J,Protein-tyrosine phosphatase pi,Pancreatic carcinoma phosphatase 2,Receptor-type tyrosine-protein phosphatase U
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
PTPRU
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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