Human Receptor-type tyrosine-protein phosphatase U (PTPRU) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Human Receptor-type tyrosine-protein phosphatase U (PTPRU) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx540772
tested applications
ELISA
Description
Human Receptor-type tyrosine-protein phosphatase U (PTPRU) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Receptor-type tyrosine-protein phosphatase U (PTPRU) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Receptor-type tyrosine-protein phosphatase U (PTPRU) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q92729 |
| OMIM | 602454 |
| Alias | FMI,PTP,PCP-2,PTP-J,PTPRO,PTPU2,PTP-PI,PTP-RO,PTPPSI,hPTP-J,R-PTP-U,R-PTP-PSI,Protein-tyrosine phosphatase receptor omicron,Receptor-type protein-tyrosine phosphatase psi,Protein-tyrosine phosphatase J,Protein-tyrosine phosphatase pi,Pancreatic carcinoma phosphatase 2,Receptor-type tyrosine-protein phosphatase U |
| Background | Elisa kits for PTPRU |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
PTPRU, also known as RPTPρ, is a receptor-like protein tyrosine phosphatase that regulates cell adhesion, migration, and differentiation. It contains extracellular immunoglobulin (Ig)-like and fibronectin type III domains, a transmembrane segment, and two intracellular phosphatase domains, with the first domain being enzymatically active. PTPRU is expressed in epithelial tissues, the nervous system, and during embryonic development. It interacts with cadherins and β-catenin, mediating cell adhesion and cytoskeletal organization. PTPRU regulates Wnt/β-catenin signaling, playing a role in cellular proliferation, differentiation, and tissue development. Its expression is developmentally regulated, and dysregulation has been linked to tumor progression in various cancers, including colorectal and breast cancer. PTPRU is also implicated in stem cell maintenance and differentiation, underscoring its importance in tissue homeostasis and development. Its ability to influence cellular adhesion and signaling makes it relevant for understanding cancer and developmental biology.
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