Human Ras-related protein Rab-40B (RAB40B) ELISA Kit

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715€ (96 tests)

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935106861
info@markelab.com
name
Human Ras-related protein Rab-40B (RAB40B) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx541498
tested applications
ELISA

Description

Human Ras-related protein Rab-40B (RAB40B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Ras-related protein Rab-40B (RAB40B) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Ras-related protein Rab-40B (RAB40B)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q12829
Gene ID
10966
Alias
RAR,SEC4L,SOCS box-containing protein RAR,Protein Rar,Ras-related protein Rab-40B
Background
Elisa kits for RAB40B
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

RAB40B, member RAS oncogene family (RAB40B) is another member of the RAB GTPase family and shares many functions with other RAB proteins in regulating vesicular trafficking within the cell. RAB40B specifically aids in the sorting and transport of vesicles, ensuring that cellular components are directed to their proper locations, including the recycling of proteins and lipids between compartments. This regulation is vital for maintaining cellular processes such as signal transduction, protein synthesis, and receptor recycling. RAB40B is particularly involved in regulating the trafficking of specific cargo between the endosomes, lysosomes, and the plasma membrane, which ensures the proper processing of membrane-bound proteins. Furthermore, RAB40B contributes to cellular processes like endocytosis, where external signals and molecules are internalized by the cell for further processing. Disruptions in RAB40B’s function have been implicated in cancer, where abnormal vesicular trafficking and receptor signaling contribute to tumorigenesis. Its role in cellular trafficking also connects RAB40B to neurodegenerative diseases, where impaired vesicular recycling and dysfunction in autophagy lead to the accumulation of damaged proteins, contributing to neuronal degeneration.

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