Human Ras-related protein Rab-39B (RAB39B) ELISA Kit

Human Ras-related protein Rab-39B (RAB39B) ELISA Kit
715€ (96 tests)

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Name
Human Ras-related protein Rab-39B (RAB39B) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx541492
Tested Applications
ELISA

Description

Human Ras-related protein Rab-39B (RAB39B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Ras-related protein Rab-39B (RAB39B) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Ras-related protein Rab-39B (RAB39B)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q96DA2
Alias
WSN,BGMR,WSMN,MRX72,XLID72,Ras-related protein Rab-39B
Background
Elisa Kits for: RAB39B
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

RAB39B, member RAS oncogene family (RAB39B) is a member of the RAB GTPase family that plays a crucial role in intracellular vesicular trafficking. Specifically, RAB39B regulates the movement of vesicles between the Golgi apparatus and other cellular compartments. This protein is involved in maintaining cellular homeostasis by ensuring the proper sorting and recycling of proteins, lipids, and other essential cellular cargo. RAB39B has also been shown to be involved in the regulation of synaptic vesicle trafficking in neurons, influencing the release of neurotransmitters and the recycling of synaptic vesicles. Its function in the nervous system is essential for neuronal communication and synaptic plasticity. Dysregulation of RAB39B has been linked to neurodevelopmental disorders, particularly intellectual disabilities and autism spectrum disorders, as its malfunction can impair vesicular trafficking and neural communication, resulting in cognitive and behavioral deficits. Furthermore, RAB39B’s involvement in cellular signaling and membrane dynamics suggests that it may also contribute to other pathologies such as neurodegenerative diseases.

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