Human Ras-related protein Rab-14 (RAB14) ELISA Kit

Product specifications

ELISA Kits

Ras-related protein Rab-14 (RAB14)

Human

Colorimetric

Quantitative

Sandwich

0.78 ng/ml - 50 ng/ml

Optimal dilutions/concentrations should be determined by the end user.

96 tests

Lyophilized

ELISA

Tissue homogenates, cell lysates and other biological fluids.

Shipped within 5-12 working days. The validity for this kit is 6 months.

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

No

P61106

FBP,RAB-14,Ras-related protein Rab-14

Elisa kits for RAB14

RUO

Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

RAB14, member RAS oncogene family (RAB14) is another GTPase that regulates vesicle trafficking, particularly in the movement of vesicles between endosomes and the plasma membrane RAB14 is involved in processes such as the recycling of internalized receptors, which is important for maintaining proper cell surface protein levels and ensuring efficient signaling pathways It also plays a role in regulating endosome dynamics and sorting, contributing to the proper functioning of lysosomes and autophagy pathways RAB14 has been shown to be important for cell adhesion and migration, as it influences the transport of integrins and other key membrane proteins involved in these processes Additionally, RAB14 is implicated in regulating immune cell function, where it contributes to the trafficking of immune receptors and cytokines, playing a role in inflammation and immune responses Dysregulation of RAB14 is associated with several diseases, including cancer, where altered vesicular trafficking can contribute to tumor metastasis and resistance to treatment Further, RAB14’s role in vesicular transport and receptor recycling makes it a significant factor in cellular homeostasis and the regulation of various signaling pathways

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