Human Ras GTPase Activating Protein 1 (RASA1) Protein

Product Graph
234€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Human Ras GTPase Activating Protein 1 (RASA1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166061
tested applications
WB, SDS-PAGE

Description

Human Ras GTPase Activating Protein 1 is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Ras GTPase Activating Protein 1 (RASA1)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 26.5 kDa

Concentration: Prior to lyophilization: 100 µg/ml

Sequence Fragment: Pro403-Leu596

Tag: N-terminal His tag
Expression
Recombinant
Purity
> 90%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P20936
Gene ID
5921
OMIM
139150
Background
Protein RASA1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Related Products

FNab07128

RASA1 antibody

Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21; this stimulation may be further increased in the presence of NCK1.

Ver Producto
abx001377

Ras GTPase-Activating Protein 1 (RASA1) Antibody

RASA1 Antibody is a Rabbit Polyclonal antibody against RASA1. The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues. [provided by RefSeq, May 2012].

Ver Producto
abx115066

Ras GTPase-Activating Protein 1 (RASA1) Antibody

Ras P21 Protein Activator (Gtpase Activating Protein) 1 Antibody is a Rabbit Polyclonal antibody against Ras P21 Protein Activator (Gtpase Activating Protein) 1.

Ver Producto