Human RAR Related Orphan Receptor Gamma (RORg) Protein
234€ (10 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human RAR Related Orphan Receptor Gamma (RORg) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx068825
Tested Applications
WB, SDS-PAGE
Description
Human RAR Related Orphan Receptor Gamma (RORg) is a recombinant Human protein expressed in E. coli.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | RAR Related Orphan Receptor Gamma (RORg) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Glu212-Ser461 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 32.5 kDa Observed MW (SDS-PAGE): 32 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | P51449 |
| Alias | TOR,RORG,RZRG,IMD42,NR1F, RZR-GAMMA,Nuclear receptor ROR-gamma,RAR-related orphan receptor C,Nuclear receptor subfamily 1 group F member 3 |
| Background | Protein RORC |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Background
RAR related orphan receptor C (RORC), also known as RORγ, is a nuclear receptor that plays a crucial role in regulating immune responses, particularly in the differentiation of Th17 cells, which are a subset of helper T cells involved in autoimmune diseases RORC is essential for the regulation of inflammatory processes and the production of pro-inflammatory cytokines, making it a key player in the pathogenesis of conditions like rheumatoid arthritis, psoriasis, and multiple sclerosis RORC also influences the development of the thymus and other immune organs, playing a role in maintaining immune homeostasis It is involved in the regulation of metabolic processes and the response to oxidative stress and environmental factors Dysregulation of RORC expression is linked to autoimmune diseases, chronic inflammation, and cancer, where altered immune regulation contributes to disease progression Targeting RORC with specific inhibitors has been explored as a therapeutic strategy to manage autoimmune diseases and inflammatory conditions, highlighting its potential as a drug target in immune-related therapies
Productos relacionados
RAR Related Orphan Receptor Gamma (RORG) Antibody
Rabbit polyclonal antibody against RORG protein. Immunogen region is Internal.…
Ver producto
Human RAR Related Orphan Receptor Gamma (RORg) Protein
Human RAR Related Orphan Receptor Gamma (RORg) is a recombinant Human protein expressed in E. coli.…
Ver producto
RAR Related Orphan Receptor Gamma (RORg) Antibody
Polyclonal Antibody to RAR Related Orphan Receptor Gamma (RORg).…
Ver producto