Human RAR Related Orphan Receptor Beta (RORb) ELISA Kit
715€ (96 tests)
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Name
Human RAR Related Orphan Receptor Beta (RORb) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx382880
Tested Applications
ELISA
Description
Human RAR Related Orphan Receptor Beta (RORb) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human RORB concentrations in tissue homogenates, cell lysates and other biological fluids.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | RAR Related Orphan Receptor Beta (RORb) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.188 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q92753 |
| OMIM | 601972 |
| Alias | RZRB,EIG15,NR1F2,RORbeta,ROR-BETA,RZR-BETA,Nuclear receptor ROR-beta,Nuclear receptor RZR-beta,Nuclear receptor subfamily 1 group F member 2 |
| Background | Elisa Kits for: RORB |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
RAR related orphan receptor B (RORB) is another member of the ROR family of nuclear receptors, playing a critical role in regulating the development of the central nervous system and circadian rhythms RORB is particularly important for the development of the retina and the regulation of visual processing, where it modulates the expression of genes involved in retinal cell differentiation and function It also participates in regulating the transcription of genes related to metabolism and cell growth, affecting cellular differentiation in multiple tissues RORB is involved in the regulation of sleep-wake cycles by modulating the circadian clock and influencing the expression of key clock genes Disruption in RORB expression is linked to several neurological disorders, including sleep disturbances and retinal degeneration, and may contribute to diseases like bipolar disorder and schizophrenia Its role in neurodevelopment and circadian regulation makes RORB a target for therapies aimed at treating neurological diseases and circadian rhythm disorders
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