Human RAR Related Orphan Receptor Alpha (RORa) ELISA Kit

Este producto es parte de RAR related orphan receptor
Human RAR Related Orphan Receptor Alpha (RORa) ELISA Kit
715€ (96 tests)

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Name
Human RAR Related Orphan Receptor Alpha (RORa) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx258568
Tested Applications
ELISA

Description

Human RAR Related Orphan Receptor Alpha (RORa) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human RAR Related Orphan Receptor Alpha concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
RAR Related Orphan Receptor Alpha (RORa)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
< 0.06 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
ROR1,ROR2,ROR3,RZRA,NR1F1,RORa1,IDDECA,RORalpha,RZR-ALPHA,Nuclear receptor ROR-alpha,Nuclear receptor subfamily 1 group F member 1,Retinoid-related orphan receptor-alpha
Background
Elisa Kits for: RORA
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

RAR related orphan receptor A (RORA) is a nuclear receptor that is involved in regulating circadian rhythms, neurodevelopment, and immune system function RORA is activated by retinoic acid, but unlike classic retinoic acid receptors, it is considered an "orphan" receptor due to its lack of well-characterized endogenous ligands RORA plays a crucial role in maintaining the body’s internal clock, influencing sleep-wake cycles and regulating the expression of genes involved in metabolic processes It is also involved in brain function, particularly in the regulation of cerebellar development and the formation of neural circuits Additionally, RORA influences immune system function, where it helps modulate inflammatory responses and autoimmunity Dysregulation of RORA has been associated with various diseases, including neurodegenerative diseases, autoimmune disorders, and psychiatric conditions like autism spectrum disorder and depression

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