Human RAB8B, Member RAS Oncogene Family (RAB8B) ELISA Kit
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Human RAB8B, Member RAS Oncogene Family (RAB8B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human RAB8B concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | RAB8B, Member RAS Oncogene Family (RAB8B) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q92930 |
| Gene ID | 51762 |
| OMIM | 613532 |
| Alias | Ras-related protein Rab-8B |
| Background | Elisa kits for RAB8B |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
RAB8B, member RAS oncogene family (RAB8B) is closely related to RAB8A and shares many functions in vesicular trafficking, cell polarization, and synaptic function RAB8B is involved in the trafficking of vesicles between the Golgi apparatus and the plasma membrane, contributing to the delivery of membrane proteins and receptors to the cell surface RAB8B also regulates the movement of vesicles in other processes such as ciliogenesis and neuronal development, where it helps organize cellular structures like cilia and dendritic spines It has been implicated in cellular signaling pathways that influence growth, survival, and migration, particularly in response to environmental stimuli Similar to RAB8A, disruptions in RAB8B have been associated with neurodegenerative diseases, where impaired vesicular transport leads to dysfunction in synaptic activity and cell signaling Additionally, RAB8B plays a role in cellular responses to stress, and its dysregulation is associated with cancer, where changes in vesicular trafficking contribute to tumor growth and metastasis
Related Products
Human RAB8B (Ras-related protein Rab-8B) ELISA Kit
Ver Producto
RAB8B antibody
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells(By similarity).
Ver ProductoRAB8B antibody
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells(By similarity).
Ver Producto