The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in polarized vesicular trafficking and neurotransmitter release. May participate in cell junction dynamics in Sertoli cells(By similarity).
Primary Antibodies
polyclonal
human,mouse
RAB8B, member RAS oncogene family
Rabbit
IgG
Unconjugated
liquid
ELISA, IHC, WB, IP
24 kDa
≥95% as determined by SDS-PAGE
Immunogen affinity purified
WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:500
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
RAB8B
Ras-related protein Rab-8B
This product is for research use only.
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