Human RAB39B, Member RAS Oncogene Family (RAB39B) Protein

234€ (5 µg)
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name
Human RAB39B, Member RAS Oncogene Family (RAB39B) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680311
tested applications
SDS-PAGE
Description
Human RAB39B, Member RAS Oncogene Family (RAB39B) Protein is a recombinant protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | RAB39B, Member RAS Oncogene Family (RAB39B) |
Host | E. coli |
Origin | Human |
Conjugation | Unconjugated |
Expression | Recombinant |
Purity | > 90% (SDS-PAGE) |
Size 1 | 5 µg |
Size 2 | 20 µg |
Size 3 | 1 mg |
Form | Liquid |
Tested Applications | SDS-PAGE |
Availability | Shipped within 5-10 working days. |
Dry Ice | No |
Alias | WSN,BGMR,WSMN,MRX72,XLID72,Ras-related protein Rab-39B |
Background | Protein RAB39B |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
RAB39B, member RAS oncogene family (RAB39B) is a member of the RAB GTPase family that plays a crucial role in intracellular vesicular trafficking. Specifically, RAB39B regulates the movement of vesicles between the Golgi apparatus and other cellular compartments. This protein is involved in maintaining cellular homeostasis by ensuring the proper sorting and recycling of proteins, lipids, and other essential cellular cargo. RAB39B has also been shown to be involved in the regulation of synaptic vesicle trafficking in neurons, influencing the release of neurotransmitters and the recycling of synaptic vesicles. Its function in the nervous system is essential for neuronal communication and synaptic plasticity. Dysregulation of RAB39B has been linked to neurodevelopmental disorders, particularly intellectual disabilities and autism spectrum disorders, as its malfunction can impair vesicular trafficking and neural communication, resulting in cognitive and behavioral deficits. Furthermore, RAB39B’s involvement in cellular signaling and membrane dynamics suggests that it may also contribute to other pathologies such as neurodegenerative diseases.
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