Human RAB1A, Member RAS Oncogene Family (RAB1A) Protein
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Description
Human RAB1A Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | RAB1A, Member RAS Oncogene Family (RAB1A) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 26.2 kDa Observed MW (SDS-PAGE): 26 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser2-Cys205 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P62820 |
| Alias | RAB1,YPT1,Ras-related protein Rab-1A,YPT1-related protein |
| Background | Protein RAB1A |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
RAB1A, member RAS oncogene family (RAB1A) is a small GTPase that is part of the RAS superfamily, which is involved in regulating intracellular vesicular trafficking, including the transport of proteins and lipids between cellular compartments RAB1A controls the transport of materials from the endoplasmic reticulum (ER) to the Golgi apparatus, which is crucial for protein sorting and secretion Additionally, RAB1A plays a role in regulating cellular processes such as cell proliferation, division, and apoptosis through its involvement in vesicle formation and membrane dynamics Dysregulation of RAB1A can lead to a range of diseases, including cancer, where its aberrant activity contributes to uncontrolled cell growth and metastasis Furthermore, RAB1A has been linked to diseases involving defects in protein trafficking, such as neurodegenerative diseases, highlighting its importance in both normal cellular functions and disease pathogenesis
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