Human PTPRF (Receptor-type tyrosine-protein phosphatase F) ELISA Kit

Este producto es parte de PTPR - protein tyrosine phosphatase receptor type
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935106861
info@markelab.com
name
Human PTPRF (Receptor-type tyrosine-protein phosphatase F) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH2492
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Human
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
31.25-2000pg/ml
Sensitivity
18.75pg/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
P10586
Alias
LAR,BNAH2,Leukocyte common antigen related,Receptor-type tyrosine-protein phosphatase F
Background
Elisa kits for PTPRF
Status
RUO

PTPRF, also known as leukocyte common antigen-related (LAR) protein, is a receptor-like protein tyrosine phosphatase involved in cell-cell adhesion, neuronal development, and tissue organization. Structurally, PTPRF contains extracellular immunoglobulin-like (Ig) domains, fibronectin type III domains, a single transmembrane region, and two intracellular phosphatase domains, where the first exhibits enzymatic activity. PTPRF plays a critical role in synaptic formation, axonal guidance, and neuronal differentiation through interactions with ligands like netrin-G ligands and heparan sulfate proteoglycans. It regulates focal adhesion and cytoskeletal organization by interacting with intracellular proteins such as liprin-α. Mutations or dysregulation of PTPRF have been implicated in cancers, insulin resistance, and neurological disorders, including intellectual disability and autism.

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