Human PTPRF(Receptor-type tyrosine-protein phosphatase F) ELISA Kit

Este producto es parte de PTPR - protein tyrosine phosphatase receptor type
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935106861
info@markelab.com
name
Human PTPRF(Receptor-type tyrosine-protein phosphatase F) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH2492

Documents del producto

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Data sheet

Product specifications

CategoryELISA Kits
Reactivityhuman
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich ELISA, Double Antibody
Test Range0.781-50ng/ml
Size 196T
Sample TypeSerum,Plasma,Tissue homogenates,Other biological fluids
AvailabilityShipped within 10-14 working days.
Storage2-8 °C for 6 months
UniProt IDP10586
AliasLAR,BNAH2,Leukocyte common antigen related,Receptor-type tyrosine-protein phosphatase F
BackgroundElisa Kits PTPRF
StatusRUO

PTPRF, also known as leukocyte common antigen-related (LAR) protein, is a receptor-like protein tyrosine phosphatase involved in cell-cell adhesion, neuronal development, and tissue organization. Structurally, PTPRF contains extracellular immunoglobulin-like (Ig) domains, fibronectin type III domains, a single transmembrane region, and two intracellular phosphatase domains, where the first exhibits enzymatic activity. PTPRF plays a critical role in synaptic formation, axonal guidance, and neuronal differentiation through interactions with ligands like netrin-G ligands and heparan sulfate proteoglycans. It regulates focal adhesion and cytoskeletal organization by interacting with intracellular proteins such as liprin-α. Mutations or dysregulation of PTPRF have been implicated in cancers, insulin resistance, and neurological disorders, including intellectual disability and autism.

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