Human PTH1R (PaRathyroid hormone/paRathyroid hormone-related peptide receptor) ELISA Kit
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human PTH1R (PaRathyroid hormone/paRathyroid hormone-related peptide receptor) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH15067
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.156-10ng/ml |
| Sensitivity | 0.094ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | Q03431 |
| Alias | PTH1R,PPR,PTHR,PTHR1,EKNS, PFE |
| Background | Elisa kits for PTH1R |
| Status | RUO |
Background
PTH1R is a G protein-coupled receptor activated by parathyroid hormone (PTH) and parathyroid hormone-related peptide (PTHrP). It is primarily expressed in bone, kidney, and cartilage, where it regulates calcium and phosphate homeostasis, bone remodeling, and cartilage development. PTH1R couples to both Gs and Gq proteins, leading to activation of adenylate cyclase (increasing cAMP) and phospholipase C (PLC) pathways. In bone, PTH1R mediates osteoblast activation, enhancing bone formation and resorption in response to PTH. In the kidney, PTH1R regulates calcium reabsorption and phosphate excretion to maintain calcium balance. Dysregulation of PTH1R signaling is associated with hyperparathyroidism, hypoparathyroidism, and bone diseases like osteoporosis. PTH analogs that target PTH1R are used therapeutically to treat osteoporosis and hypoparathyroidism by promoting bone growth and mineral homeostasis. PTH1R’s essential role in calcium regulation and skeletal health makes it a key target for metabolic bone diseases.
Productos relacionados
Parathyroid Hormone Receptor 1 (PTH1R) Antibody
PTH1R Antibody is a Rabbit Polyclonal antibody against PTH1R. The protein encoded by this gene is a member of the G-prot…
Ver producto
Parathyroid Hormone Receptor 1 (PTH1R) Antibody
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for …
Ver producto
Human Parathyroid Hormone Receptor 1 (PTH1R) ELISA Kit
Human Parathyroid Hormone Receptor 1 (PTH1R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Huma…
Ver producto