Human Protein VPRBP (DCAF1) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Protein VPRBP (DCAF1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx553123
tested applications
ELISA
Description
Human Protein VPRBP (DCAF1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Protein VPRBP (DCAF1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Protein VPRBP (DCAF1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9Y4B6 |
| Alias | RIP,VPRBP,KIAA0800,Vpr-interacting protein,Serine/threonine-protein kinase VPRBP,HIV-1 Vpr-binding protein |
| Background | Elisa kits for DCAF1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
DDB1 and CUL4 associated factor 1 (DCAF1), also known as VprBP, is a multifunctional protein that serves as a substrate receptor within the CUL4-DDB1 E3 ubiquitin ligase complex. It plays a pivotal role in various cellular processes, including cell cycle regulation, telomerase activity, and histone modification. DCAF1's interaction with the HIV-1 accessory protein Vpr has been extensively studied, revealing its involvement in viral pathogenesis. Structurally, DCAF1 contains WD40 repeats that facilitate protein-protein interactions, enabling it to recruit specific substrates for ubiquitination. Its expression is ubiquitous, with notable presence in the nucleoplasm and nucleoli fibrillar center, indicating its involvement in nuclear functions. DCAF1's kinase activity, particularly its ability to phosphorylate histone H2A at threonine 120, underscores its role in transcriptional regulation. Additionally, DCAF1 is implicated in the regulation of microRNA biogenesis and the development and function of B and T lymphocytes, highlighting its significance in both general and cell type-specific processes.
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Human Protein VPRBP (DCAF1) ELISA Kit
Human Protein VPRBP (DCAF1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Protein VPRBP (DCAF1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Ver Producto