Human Protein Tyrosine Phosphatase Receptor Type B (PTPRB) ELISA Kit

Este producto es parte de PTPR - protein tyrosine phosphatase receptor type
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611€ (96 tests)

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935106861
info@markelab.com
name
Human Protein Tyrosine Phosphatase Receptor Type B (PTPRB) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx351479
tested applications
ELISA

Description

Human Protein Tyrosine Phosphatase Receptor Type B (PTPRB) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human PTPRB concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetProtein Tyrosine Phosphatase Receptor Type B (PTPRB)
ReactivityHuman
Detection MethodColorimetric
Assay DataQuantitative
Assay TypeSandwich
Test Range0.312 ng/ml - 20 ng/ml
Sensitivity0.19 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
Size 25 × 96 tests
Size 310 × 96 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDP23467
AliasPTPB,HPTPB,VEPTP,HPTP-BETA,R-PTP-BETA,Vascular endothelial protein tyrosine phosphatase,Protein-tyrosine phosphatase beta,Receptor-type tyrosine-protein phosphatase beta
BackgroundElisa kits for PTPRB
StatusRUO
NoteValidity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

PTPRB is a member of the receptor-type protein tyrosine phosphatases (RPTPs), which regulate tyrosine phosphorylation-dependent signaling. PTPRB plays an essential role in vascular development and endothelial cell function. It has an extracellular domain, a transmembrane region, and two intracellular phosphatase domains, of which one is enzymatically active. PTPRB is expressed predominantly in endothelial cells and modulates vascular permeability, angiogenesis, and blood vessel remodeling. It is involved in suppressing VEGF receptor signaling to maintain endothelial quiescence. Dysregulation of PTPRB has been implicated in diseases such as vascular malformations and cancers involving aberrant angiogenesis.

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