Human Protein Tyrosine Phosphatase Receptor Type B (PTPRB) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
587.5€ (96 tests)
Elisa Kits PTPRB
proveedor
Abbexareference
abx351479Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Protein Tyrosine Phosphatase Receptor Type B (PTPRB) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human PTPRB concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
PTPRB is a member of the receptor-type protein tyrosine phosphatases (RPTPs), which regulate tyrosine phosphorylation-dependent signaling. PTPRB plays an essential role in vascular development and endothelial cell function. It has an extracellular domain, a transmembrane region, and two intracellular phosphatase domains, of which one is enzymatically active. PTPRB is expressed predominantly in endothelial cells and modulates vascular permeability, angiogenesis, and blood vessel remodeling. It is involved in suppressing VEGF receptor signaling to maintain endothelial quiescence. Dysregulation of PTPRB has been implicated in diseases such as vascular malformations and cancers involving aberrant angiogenesis.
Características del producto
category
ELISA Kits
immunogen target
Protein Tyrosine Phosphatase Receptor Type B (PTPRB)
reactivity
Human
test range
0.312 ng/ml - 20 ng/ml
sensitivity
0.19 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
PTPB,HPTPB,VEPTP,HPTP-BETA,R-PTP-BETA,Vascular endothelial protein tyrosine phosphatase,Protein-tyrosine phosphatase beta,Receptor-type tyrosine-protein phosphatase beta
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
PTPRB
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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