Human Protein AHNAK2 (AHNAK2) ELISA Kit

Este producto es parte de AHNAK - AHNAK nucleoprotein
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Protein AHNAK2 (AHNAK2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501322
tested applications
ELISA

Description

Human Protein AHNAK2 (AHNAK2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Protein AHNAK2 (AHNAK2) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
Protein AHNAK2 (AHNAK2)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.312 ng/ml - 20 ng/ml
Sensitivity
< 0.16 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q8IVF2
OMIM
608570
Alias
C14orf78
Background
Elisa kits for AHNAK2
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

AHNAK2 is a homolog of AHNAK with similar structural and functional characteristics. It is a large, scaffold-like protein involved in cytoskeletal organization, cell-cell adhesion, and calcium-dependent signaling pathways. AHNAK2 is expressed in various tissues, including the epithelial lining and tumor cells, where it participates in regulating membrane dynamics and cellular integrity. Emerging research highlights its role in tumor biology, with elevated AHNAK2 expression observed in cancers such as renal cell carcinoma, lung adenocarcinoma, and pancreatic cancer, where it promotes tumor growth, invasion, and chemoresistance. AHNAK2 also appears to be involved in epithelial-to-mesenchymal transition (EMT), a key process in cancer metastasis. While its specific roles in normal physiology are less understood compared to AHNAK, its overexpression in malignancies makes it a promising diagnostic marker and potential therapeutic target.

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