Human Prostaglandin-H2 D-Isomerase (PTGDS) Protein
234€ (2 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Prostaglandin-H2 D-Isomerase (PTGDS) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx073703
tested applications
SDS-PAGE
Description
Prostaglandin D2 Synthase is a recombinant enzyme.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Prostaglandin-H2 D-Isomerase (PTGDS) |
| Host | E. coli |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Human |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P41222 |
| Background | Protein PTGDS |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Prostaglandin D2 Synthase (PTGDS) is an enzyme that catalyzes the isomerization of prostaglandin H2 (PGH2) to prostaglandin D2 (PGD2), a key lipid mediator involved in sleep regulation, allergic inflammation, vasodilation, and immune modulation PTGDS is highly expressed in the brain, heart, and male reproductive organs, where it participates in cerebrospinal fluid production, detoxification of free radicals, and maintenance of male fertility PGD2 plays a central role in allergic reactions, mediating bronchoconstriction in asthma and inflammation in rhinitis Dysregulation of PTGDS contributes to neurological disorders such as Alzheimer’s disease by facilitating tau phosphorylation, amyloid deposition, and oxidative stress PTGDS also serves as a biomarker for cardiovascular disease, brain injury, and central nervous system inflammation Its role in lipid signaling and antioxidant defense highlights its importance in both homeostasis and disease progression
Related Products
PTGDS antibody
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
Ver Producto
Recombinant Human PTGDS
Ver Producto
Prostaglandin-H2 D-Isomerase (PTGDS) Antibody
PTGDS Antibody is a Rabbit Polyclonal Antibody against PTGDS.
Ver Producto