Human Prostaglandin-H2 D-isomerase (PTGDS) ELISA Kit

Este producto es parte de PTGDS - Prostaglandin D2 Synthase
Human Prostaglandin-H2 D-isomerase (PTGDS) ELISA Kit
611€ (96 tests)

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Name
Human Prostaglandin-H2 D-isomerase (PTGDS) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx252947
Tested Applications
ELISA

Description

Human Prostaglandin-H2 D-isomerase (PTGDS) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Prostaglandin-H2 D-isomerase (PTGDS) concentrations in serum, plasma and other biological fluids.

Documentos del producto

Instrucciones
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Data sheet
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Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Prostaglandin-H2 D-isomerase (PTGDS)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
62.5 pg/ml - 4000 pg/ml
Sensitivity
37.5 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P41222
OMIM
176803
Background
Elisa Kits for: PTGDS
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

Prostaglandin D2 Synthase (PTGDS) is an enzyme that catalyzes the isomerization of prostaglandin H2 (PGH2) to prostaglandin D2 (PGD2), a key lipid mediator involved in sleep regulation, allergic inflammation, vasodilation, and immune modulation PTGDS is highly expressed in the brain, heart, and male reproductive organs, where it participates in cerebrospinal fluid production, detoxification of free radicals, and maintenance of male fertility PGD2 plays a central role in allergic reactions, mediating bronchoconstriction in asthma and inflammation in rhinitis Dysregulation of PTGDS contributes to neurological disorders such as Alzheimer’s disease by facilitating tau phosphorylation, amyloid deposition, and oxidative stress PTGDS also serves as a biomarker for cardiovascular disease, brain injury, and central nervous system inflammation Its role in lipid signaling and antioxidant defense highlights its importance in both homeostasis and disease progression

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