Human Programmed Cell Death 1 Ligand 1 (CD274) Protein

234€ (2 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Programmed Cell Death 1 Ligand 1 (CD274) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680008
tested applications
SDS-PAGE
Description
Human Programmed Cell Death 1 Ligand 1 (CD274) Protein is a recombinant protein produced in Sf9, Baculovirus cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Programmed Cell Death 1 Ligand 1 (CD274) |
Host | Insect |
Origin | Human |
Conjugation | Unconjugated |
Expression | Recombinant |
Purity | > 95% (SDS-PAGE) |
Size 1 | 2 µg |
Size 2 | 10 µg |
Size 3 | 100 µg |
Form | Liquid |
Tested Applications | SDS-PAGE |
Availability | Shipped within 5-10 working days. |
Dry Ice | No |
Alias | B7-H,B7H1,PDL,PD-L1,hPD-L1,PDCD1L1,PDCD1LG1,B7 homolog 1,PDCD1 ligand 1,Programmed death ligand 1,Programmed cell death 1 ligand 1 |
Background | Protein CD274 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CD274 molecule, also known as Programmed Death-Ligand 1 (PD-L1), is a critical component in the immune checkpoint pathway. Encoded by the CD274 gene located on chromosome 9p24.1, PD-L1 is primarily expressed on the surface of various cell types, including immune cells (such as T cells, B cells, dendritic cells, and macrophages) and non-immune cells (including epithelial and endothelial cells). Its expression can be upregulated in response to inflammatory signals, particularly interferon-gamma (IFN-γ). PD-L1 plays a vital role in maintaining immune homeostasis and preventing autoimmunity by regulating the activity of T cells. PD-L1 gained significant attention in cancer immunotherapy due to its role in tumor immune evasion. Many tumors exploit the PD-1/PD-L1 pathway to suppress anti-tumor immune responses, allowing cancer cells to escape immune surveillance
Related Products

APC Anti-Mouse CD274(10F.9G2)
Ver Producto
APC Anti-Human CD274(29E.2A3)
Ver Producto