Human Programmed Cell Death 1 Ligand 1 (CD274) Protein

Este producto es parte de CD274 molecule
Product Graph
234€ (2 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Human Programmed Cell Death 1 Ligand 1 (CD274) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680008
tested applications
SDS-PAGE

Description

Human Programmed Cell Death 1 Ligand 1 (CD274) Protein is a recombinant protein produced in Sf9, Baculovirus cells.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Programmed Cell Death 1 Ligand 1 (CD274)
Host
Insect
Origin
Human
Conjugation
Unconjugated
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
2 µg
Size 2
10 µg
Size 3
100 µg
Form
Liquid 
Tested Applications
SDS-PAGE
Availability
Shipped within 5-10 working days.
Dry Ice
No
Alias
B7-H,B7H1,PDL,PD-L1,hPD-L1,PDCD1L1,PDCD1LG1,B7 homolog 1,PDCD1 ligand 1,Programmed death ligand 1,Programmed cell death 1 ligand 1
Background
Protein CD274
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

CD274 molecule, also known as Programmed Death-Ligand 1 (PD-L1), is a critical component in the immune checkpoint pathway. Encoded by the CD274 gene located on chromosome 9p24.1, PD-L1 is primarily expressed on the surface of various cell types, including immune cells (such as T cells, B cells, dendritic cells, and macrophages) and non-immune cells (including epithelial and endothelial cells). Its expression can be upregulated in response to inflammatory signals, particularly interferon-gamma (IFN-γ). PD-L1 plays a vital role in maintaining immune homeostasis and preventing autoimmunity by regulating the activity of T cells. PD-L1 gained significant attention in cancer immunotherapy due to its role in tumor immune evasion. Many tumors exploit the PD-1/PD-L1 pathway to suppress anti-tumor immune responses, allowing cancer cells to escape immune surveillance

Related Products

APC-30030

APC Anti-Mouse CD274(10F.9G2)

Ver Producto
APC-30044

APC Anti-Human CD274(29E.2A3)

Ver Producto
EM0399

Mouse CD274 (Programmed cell death 1 ligand 1) ELISA Kit

Ver Producto