Human Programmed Cell Death 1 Ligand 1 (CD274) ELISA Kit

Este producto es parte de CD274 molecule
Human Programmed Cell Death 1 Ligand 1 (CD274) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

600€ (96 tests)

Elisa Kits CD274

proveedor

Abbexa

reference

abx258720

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Programmed Cell Death Protein 1 Ligand 1 / PD-L1 (CD274) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Programmed Cell Death Protein 1 Ligand 1 / PD-L1 (CD274) concentrations in tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.


Background

CD274 molecule, also known as Programmed Death-Ligand 1 (PD-L1), is a critical component in the immune checkpoint pathway. Encoded by the CD274 gene located on chromosome 9p24.1, PD-L1 is primarily expressed on the surface of various cell types, including immune cells (such as T cells, B cells, dendritic cells, and macrophages) and non-immune cells (including epithelial and endothelial cells). Its expression can be upregulated in response to inflammatory signals, particularly interferon-gamma (IFN-γ). PD-L1 plays a vital role in maintaining immune homeostasis and preventing autoimmunity by regulating the activity of T cells. PD-L1 gained significant attention in cancer immunotherapy due to its role in tumor immune evasion. Many tumors exploit the PD-1/PD-L1 pathway to suppress anti-tumor immune responses, allowing cancer cells to escape immune surveillance

Características del producto

category

ELISA Kits


immunogen target

Programmed Cell Death 1 Ligand 1 (CD274)


reactivity

Human


test range

0.312 ng/ml - 20 ng/ml


sensitivity

< 0.12 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

B7-H,B7H1,PDL,PD-L1,hPD-L1,PDCD1L1,PDCD1LG1,B7 homolog 1,PDCD1 ligand 1,Programmed death ligand 1,Programmed cell death 1 ligand 1


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

CD274


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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