Human Platelet Glycoprotein 4 (CD36) CLIA Kit

Este producto es parte de CD36 - CD36 molecule
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643.5€ (96 tests)

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935106861
info@markelab.com
name
Human Platelet Glycoprotein 4 (CD36) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx195713
tested applications
CLIA

Description

Human Platelet Membrane Glycoprotein IV (GP4/CD36) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Platelet Membrane Glycoprotein IV (GP4/CD36).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
CLIA Kits
Immunogen Target
Platelet Glycoprotein 4 (CD36)
Reactivity
Human
Detection Method
Chemiluminescent
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
31.2 pg/ml - 2000 pg/ml
Sensitivity
18.8 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
CLIA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-12 working days.
Storage
 Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P16671
Alias
FAT,GP4,GP3B,GPIV,CHDS7,PASIV,SCARB3,BDPLT10,CD36 blood group,Platelet glycoprotein 4,Fatty acid translocase,Glycoprotein IIIb,GPIIIB,Leukocyte differentiation antigen CD36,PAS IV,PAS-4
Background
CLIA Kits CD36
Status
RUO
Note
The validity for this kit is 6 months.   This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

CD36, also known as platelet glycoprotein IV (GPIV) or fatty acid translocase (FAT), is a multifunctional membrane glycoprotein involved in various physiological processes, including lipid metabolism, immune response, angiogenesis, and pathogen recognition. It is a scavenger receptor, which means it can bind and internalize a wide range of ligands, including oxidized low-density lipoprotein (oxLDL), long-chain fatty acids, and apoptotic cells. CD36 is expressed in a variety of tissues, including platelets, monocytes, macrophages, adipocytes, skeletal muscle, heart muscle, and endothelial cells. CD36 is part of the class B scavenger receptor family and plays a key role in cellular lipid uptake, particularly the transport of long-chain fatty acids into cells, where they are utilized for energy production or stored as triglycerides. Additionally, CD36 has significant roles in the innate immune system, acting as a pattern recognition receptor (PRR) for various ligands, including microbial components and oxidized lipoproteins, contributing to the body's defense against infections and in the pathogenesis of chronic inflammatory conditions, such as atherosclerosis.

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