Human Platelet Glycoprotein 4 (CD36) CLIA Kit
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935106861
info@markelab.com
Precio
643.5€ (96 tests)
CLIA Kits CD36
proveedor
Abbexareference
abx195713Tested Applications
CLIAreactivity
Humanstatus
RUOclonality
Descripción
Human Platelet Membrane Glycoprotein IV (GP4/CD36) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Platelet Membrane Glycoprotein IV (GP4/CD36).
Background
CD36, also known as platelet glycoprotein IV (GPIV) or fatty acid translocase (FAT), is a multifunctional membrane glycoprotein involved in various physiological processes, including lipid metabolism, immune response, angiogenesis, and pathogen recognition. It is a scavenger receptor, which means it can bind and internalize a wide range of ligands, including oxidized low-density lipoprotein (oxLDL), long-chain fatty acids, and apoptotic cells. CD36 is expressed in a variety of tissues, including platelets, monocytes, macrophages, adipocytes, skeletal muscle, heart muscle, and endothelial cells. CD36 is part of the class B scavenger receptor family and plays a key role in cellular lipid uptake, particularly the transport of long-chain fatty acids into cells, where they are utilized for energy production or stored as triglycerides. Additionally, CD36 has significant roles in the innate immune system, acting as a pattern recognition receptor (PRR) for various ligands, including microbial components and oxidized lipoproteins, contributing to the body's defense against infections and in the pathogenesis of chronic inflammatory conditions, such as atherosclerosis.
Características del producto
category
CLIA Kits
immunogen target
Platelet Glycoprotein 4 (CD36)
reactivity
Human
test range
31.2 pg/ml - 2000 pg/ml
sensitivity
18.8 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Chemiluminescent
sample type
Serum, plasma and other biological fluids.
size 1
96 tests
alias
FAT,GP4,GP3B,GPIV,CHDS7,PASIV,SCARB3,BDPLT10,CD36 blood group,Platelet glycoprotein 4,Fatty acid translocase,Glycoprotein IIIb,GPIIIB,Leukocyte differentiation antigen CD36,PAS IV,PAS-4
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CD36
dry ice
No
uniprot id
note
The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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