Human Platelet Derived Growth Factor Receptor Like Protein (PDGFRL) Protein

Este producto es parte de PDGFR - platelet derived growth factor receptor
Human Platelet Derived Growth Factor Receptor Like Protein (PDGFRL) Protein
234€ (10 µg)

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Name
Human Platelet Derived Growth Factor Receptor Like Protein (PDGFRL) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx166225
Tested Applications
WB, SDS-PAGE

Description

Human Platelet Derived Growth Factor Receptor Like Protein is a recombinant Human protein expressed in E. coli.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Proteins and Peptides
Immunogen Target
Platelet Derived Growth Factor Receptor Like Protein (PDGFRL)
Host
E. coli
Assay Type
Activity: Not tested
Sequence Fragment: Gln22-Ser375
Tag: N-terminal His tag and GST tag
Origin
Human
Conjugation
Unconjugated
Observed MW
Calculated MW: 69.5 kDa
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles.
Dry Ice
No
Alias
PDGRL,PRLTS,PDGF receptor beta-like tumor suppressor,PDGFR-like protein
Background
Protein PDGFRL
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Concentration: Prior to lyophilization: 200 µg/ml

Background

Platelet derived growth factor receptor like (PDGFRL) lacks intrinsic kinase activity and is thought to function in the regulation of extracellular matrix components and intercellular communication although its precise role is less defined compared to PDGFRA and PDGFRB mutations in PDGFRL have been linked to tumor suppressor activity in colorectal and gastric cancers suggesting it may act as a modulator of growth factor signaling networks its reduced expression has been correlated with increased tumor invasiveness and metastasis in some cancers indicating its potential importance in maintaining cellular homeostasis ongoing research seeks to clarify its role in cellular signaling and its impact on cancer progression and therapeutic resistance.

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