Human Photoreceptor Cell Specific Nuclear Receptor / PNR (NR2E3) Protein
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935106861
info@markelab.com
Precio
225€ (10 µg)
Protein NR2E3
proveedor
Abbexareference
abx168287Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Photoreceptor Cell Specific Nuclear Receptor Protein is a recombinant Human protein expressed in E. coli.
Background
Nuclear receptor subfamily 2 group E member 3 (NR2E3), also known as photoreceptor-specific nuclear receptor, is a nuclear receptor involved in the regulation of retinal development and the function of photoreceptors in the eye NR2E3 is specifically expressed in the retina, where it regulates the differentiation of photoreceptor cells, including rods and cones It plays a critical role in the development of the retina by influencing the expression of genes involved in the differentiation and maintenance of photoreceptors, which are essential for vision NR2E3 also controls the transcriptional network that governs the survival of retinal cells and the response to light Inherited mutations in NR2E3 are associated with retinal degenerative diseases, such as retinitis pigmentosa, which leads to progressive vision loss by impairing photoreceptor function In addition, NR2E3’s role in regulating the development of other retinal cell types and maintaining visual function makes it an important factor in ocular health and a potential target for therapeutic interventions in retinal diseases
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Photoreceptor Cell Specific Nuclear Receptor / PNR (NR2E3)
host
E. coli
conjugation
Unconjugated
form
Lyophilized
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
expression
Recombinant
purity
> 90%
buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
NR2E3
dry ice
No
availability
Shipped within 5-7 working days.
alias
PNR,RNR,rd7,ESCS,RP37,Retina-specific nuclear receptor,Photoreceptor-specific nuclear receptor
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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