Human PHD Finger Protein 5A (PHF5A) ELISA Kit

Este producto es parte de PHF - PHD finger protein
Human PHD Finger Protein 5A (PHF5A) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for PHF5A

proveedor

Abbexa

reference

abx382194

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human PHD Finger Protein 5A (PHF5A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human PHF5A concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

PHF5A is a chromatin-binding protein that interacts with histones through its PHD finger domain and serves as a core component of the spliceosome complex. It regulates alternative splicing of pre-mRNA, controlling the expression of genes involved in cell cycle progression, differentiation, and apoptosis. PHF5A is essential for the recognition of splice sites and the recruitment of splicing machinery during transcription. It is ubiquitously expressed in proliferating tissues, particularly in stem cells and cancer cells, where it maintains proper gene expression programs. Dysregulation of PHF5A has been implicated in cancer, including glioblastoma and leukemia, where it promotes tumor progression by modulating splicing events that regulate survival and proliferation. Knockdown studies reveal impaired splicing, reduced cell proliferation, and increased apoptosis, underscoring its role as a critical regulator of RNA processing, transcription, and cellular growth.

Características del producto

category

ELISA Kits


immunogen target

PHD Finger Protein 5A (PHF5A)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.094 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

NI, Rds3, SAP14b, SF3B7, SF3b14b, bK223H9.2,PHD finger-like domain protein 5A


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

PHF5A


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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