Human PHD finger protein 20 (PHF20) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for PHF20
proveedor
Abbexareference
abx382192Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human PHD finger protein 20 (PHF20) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human PHF20 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
PHF20 is a chromatin-binding protein that recognizes methylated histones, particularly H3K4me3 and H4K20me1, to regulate transcriptional activation, DNA repair, and cellular proliferation. It functions as a transcriptional co-activator by recruiting epigenetic modifiers and transcription machinery to target loci, ensuring precise gene expression during development and cellular responses. PHF20 is a key regulator of p53 stability and function, linking chromatin dynamics to tumor suppression and DNA damage responses. It is expressed in proliferative tissues and plays roles in stem cell maintenance, cell cycle regulation, and DNA repair. Dysregulation of PHF20 has been implicated in cancers, where its loss of function leads to genomic instability and uncontrolled proliferation. Knockout studies demonstrate defects in p53 signaling, impaired DNA repair, and reduced cellular proliferation, highlighting its essential role in chromatin regulation, tumor suppression, and transcriptional control.
Características del producto
category
ELISA Kits
immunogen target
PHD finger protein 20 (PHF20)
reactivity
Human
test range
31.2 pg/ml - 2000 pg/ml
sensitivity
< 18.8 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
PHF20,C20orf104,GLEA2,HCA58,NZF,TZP
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
PHF20
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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