Human PHD finger protein 20 (PHF20) ELISA Kit

Este producto es parte de PHF - PHD finger protein
Human PHD finger protein 20 (PHF20) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for PHF20

proveedor

Abbexa

reference

abx382192

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human PHD finger protein 20 (PHF20) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human PHF20 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

PHF20 is a chromatin-binding protein that recognizes methylated histones, particularly H3K4me3 and H4K20me1, to regulate transcriptional activation, DNA repair, and cellular proliferation. It functions as a transcriptional co-activator by recruiting epigenetic modifiers and transcription machinery to target loci, ensuring precise gene expression during development and cellular responses. PHF20 is a key regulator of p53 stability and function, linking chromatin dynamics to tumor suppression and DNA damage responses. It is expressed in proliferative tissues and plays roles in stem cell maintenance, cell cycle regulation, and DNA repair. Dysregulation of PHF20 has been implicated in cancers, where its loss of function leads to genomic instability and uncontrolled proliferation. Knockout studies demonstrate defects in p53 signaling, impaired DNA repair, and reduced cellular proliferation, highlighting its essential role in chromatin regulation, tumor suppression, and transcriptional control.

Características del producto

category

ELISA Kits


immunogen target

PHD finger protein 20 (PHF20)


reactivity

Human


test range

31.2 pg/ml - 2000 pg/ml


sensitivity

< 18.8 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

PHF20,C20orf104,GLEA2,HCA58,NZF,TZP


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

PHF20


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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