Human Peroxisome Proliferator Activated Receptor delta (PPARD) CLIA Kit
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Description
Human Peroxisome Proliferator Activated Receptor Delta (PPAR-δ) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Peroxisome Proliferator Activated Receptor Delta (PPAR-δ).
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Product specifications
| Category | CLIA Kits |
| Immunogen Target | Peroxisome Proliferator Activated Receptor delta (PPARD) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 31.2 pg/ml - 2000 pg/ml |
| Sensitivity | 18.8 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | FAAR,NUC1,NUCI,NR1C2,NUCII,PPARB,Nuclear hormone receptor 1,Nuclear receptor subfamily 1 group C member 2 |
| Background | CLIA Kits PPARD |
| Status | RUO |
| Note | The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Peroxisome proliferator activated receptor delta (PPARD) is another member of the peroxisome proliferator-activated receptor family that regulates the expression of genes involved in lipid metabolism, energy expenditure, and inflammation PPARD is widely expressed in tissues such as the liver, muscle, and adipose tissue, where it helps regulate fatty acid oxidation, glucose metabolism, and mitochondrial function It also plays a key role in regulating the oxidative stress response and modulating the balance between energy storage and energy expenditure PPARD activation has been linked to improvements in insulin sensitivity and lipid profile, making it a potential therapeutic target for metabolic diseases like type 2 diabetes and obesity Additionally, PPARD is involved in the regulation of inflammation and immune responses, and its dysregulation has been implicated in inflammatory diseases, atherosclerosis, and certain cancers Its role in promoting fat burning and mitochondrial function makes PPARD a promising target for the development of therapies aimed at enhancing metabolic health and combating obesity-related conditions
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Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.
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anti- PPARD antibody
Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.
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