Human Pentraxin 3 (PTX3) ELISA Kit
585€ (96 tests)
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name
Human Pentraxin 3 (PTX3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx252008
tested applications
ELISA
Description
Human Pentraxin 3 (PTX3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Pentraxin 3 (PTX3) concentrations in serum, plasma and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Pentraxin 3 (PTX3) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 6.86 pg/ml - 5000 pg/ml |
| Sensitivity | 4.12 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P26022 |
| Gene ID | 5806 |
| OMIM | 602492 |
| Alias | TSG-14,TNFAIP5,Pentaxin-related protein PTX3,Tumor necrosis factor alpha-induced protein 5,TNF alpha-induced protein 5 |
| Background | Elisa Kits for: PTX3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
PTX3 is a long pentraxin and key component of the innate immune system involved in recognizing pathogens, regulating inflammation, and facilitating tissue repair PTX3 is produced by various cell types, including macrophages, neutrophils, and endothelial cells, in response to inflammatory stimuli such as IL-1β, TNF-α, and Toll-like receptor activation It acts as a soluble pattern recognition receptor (PRR), binding microbial components, such as fungal conidia, and activating complement pathways to enhance pathogen clearance PTX3 also regulates angiogenesis and extracellular matrix remodeling during tissue repair Elevated PTX3 levels are observed in conditions like sepsis, cardiovascular disease, and autoimmune disorders, where it acts as a biomarker for inflammation and disease progression PTX3 plays protective roles in infections, while dysregulated expression contributes to chronic inflammatory diseases, including atherosclerosis and rheumatoid arthritis, where it modulates both innate and adaptive immunity
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