Human Palladin (PALLD) Protein

Este producto es parte de PALLD - palladin cytoskeletal associated protein
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208€ (10 µg)

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935106861
info@markelab.com
name
Human Palladin (PALLD) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168708
tested applications
WB, SDS-PAGE

Description

Human PALLD Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryProteins and Peptides
Immunogen TargetPalladin (PALLD)
HostE. coli
OriginHuman
ConjugationUnconjugated
Observed MWMolecular Weight: Calculated MW: 30.9 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Phe1137-Leu1383 Tag: N-terminal His tag
ExpressionRecombinant
Purity> 90%
Size 110 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 5500 µg
FormLyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested ApplicationsWB, SDS-PAGE
BufferPrior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
AvailabilityShipped within 5-7 working days.
StorageStore at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ8WX93
AliasMYN,PNCA1,CGI151,SIH002,CGI-151,SIH002,Sarcoma antigen NY-SAR-80
BackgroundProtein PALLD
StatusRUO
NoteThis product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Palladin, cytoskeletal associated protein (PALLD) is a pivotal component of the cytoskeleton, playing a vital role in the organization, dynamics, and stability of actin filament networks within the cell. It acts as a scaffolding protein that binds directly to actin and other actin-associated proteins, thus facilitating the formation of stress fibers, lamellipodia, and other cellular structures critical for migration and adhesion. Palladin is especially active during developmental processes, tissue repair, and cancer metastasis, where enhanced cellular motility and structural remodeling are required. Mutations or dysregulation of PALLD have been linked to diseases such as cancer progression and certain connective tissue disorders, making it a key focus of cellular and molecular biology research.

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