Human Osteomodulin (OMD) Protein

Este producto es parte de OMD - Osteomodulin
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702€ (50 µg)

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935106861
info@markelab.com
name
Human Osteomodulin (OMD) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691802
tested applications
SDS-PAGE

Description

Human Osteomodulin Protein is a recombinant protein from Human produced in HEK293 Cells. A DNA sequence encoding the human OMD (NP_005005.1) (Met1-Glu421) was expressed with a polyhistidine tag at the C-terminus.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Osteomodulin
Host
HEK293 cells
Assay Type
Activity: Not tested
Sequence Fragment: Met1-Glu421
Tag: C-terminal His tag
Origin
Human
Observed MW
48.6 kDa
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
50 µg
Form
Lyophilized
Tested Applications
SDS-PAGE
Buffer
Lyophilized from sterile PBS, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Storage: Store lyophilized between -20 °C and -80°C.
Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months.
Shelf Life: 12 months.
Dry Ice
No
NCBI Accession
NP_005005.1
Alias
OSAD,SLRR2C,KSPG osteomodulin,Osteoadherin
Background
Protein OMD
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Endotoxin Level: < 1.0 EU per µg (LAL method).

Descripción

Osteomodulin (OMD) is a small leucine-rich proteoglycan primarily expressed in the bone and cartilage, where it plays a key role in regulating extracellular matrix (ECM) structure and function OMD is involved in bone mineralization, collagen fibril organization, and cartilage development by interacting with collagen and other ECM components It contributes to skeletal integrity and has a significant impact on the mechanical properties of bone, influencing bone strength and elasticity OMD’s expression is upregulated during bone remodeling, and its role in cartilage integrity makes it crucial for joint health and skeletal repair Dysregulation of OMD expression has been associated with bone diseases such as osteogenesis imperfecta and osteoarthritis, where altered ECM composition leads to skeletal deformities and joint degradation Studies also suggest that OMD influences cell signaling pathways, particularly those related to osteoblast differentiation and function, highlighting its broader role in skeletal development and disease
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