Human Nucleoporin NUP42 / NUPL2 (NUP42) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Nucleoporin NUP42 / NUPL2 (NUP42) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx381939
tested applications
ELISA
Description
Human Nucleoporin NUP42 / NUPL2 (NUP42) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human NUP42 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Nucleoporin NUP42 / NUPL2 (NUP42) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.16 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O15504 |
| Gene ID | 11097 |
| Alias | CG1,NLP1,UIP1,Hcg1,NLP-1,NLP_1,NUPL2,Nucleoporin-like protein 2, nucleoporin-like protein 1 |
| Background | Elisa kits for NUP42 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Nucleoporin 42 (NUP42), also known as NupL1, is a component of the nuclear pore complex (NPC), which regulates the bidirectional transport of macromolecules such as RNA and proteins between the nucleus and cytoplasm. NUP42 is specifically associated with the cytoplasmic face of the NPC and plays a critical role in mRNA export and other transport pathways. It interacts with the CRM1 export receptor, facilitating the export of certain cargoes during cellular stress responses and viral infections. Mutations or dysregulation of NUP42 can affect nucleocytoplasmic transport, contributing to cellular senescence, developmental defects, and diseases such as cancer and neurodegenerative disorders. Understanding its function provides insights into the dynamics of nuclear-cytoplasmic communication and the mechanisms underlying related pathologies.
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