Human Nucleoporin NUP42 / NUPL2 (NUP42) ELISA Kit

Este producto es parte de NUP - nucleoporin
Human Nucleoporin NUP42 / NUPL2 (NUP42) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for NUP42

proveedor

Abbexa

reference

abx381939

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Nucleoporin NUP42 / NUPL2 (NUP42) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human NUP42 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Nucleoporin 42 (NUP42), also known as NupL1, is a component of the nuclear pore complex (NPC), which regulates the bidirectional transport of macromolecules such as RNA and proteins between the nucleus and cytoplasm. NUP42 is specifically associated with the cytoplasmic face of the NPC and plays a critical role in mRNA export and other transport pathways. It interacts with the CRM1 export receptor, facilitating the export of certain cargoes during cellular stress responses and viral infections. Mutations or dysregulation of NUP42 can affect nucleocytoplasmic transport, contributing to cellular senescence, developmental defects, and diseases such as cancer and neurodegenerative disorders. Understanding its function provides insights into the dynamics of nuclear-cytoplasmic communication and the mechanisms underlying related pathologies.

Características del producto

category

ELISA Kits


immunogen target

Nucleoporin NUP42 / NUPL2 (NUP42)


reactivity

Human


test range

0.312 ng/ml - 20 ng/ml


sensitivity

< 0.16 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

CG1,NLP1,UIP1,Hcg1,NLP-1,NLP_1,NUPL2,Nucleoporin-like protein 2, nucleoporin-like protein 1


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

NUP42


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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