Human Nucleoporin NUP42 / NUPL2 (NUP42) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for NUP42
proveedor
Abbexareference
abx381939Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Nucleoporin NUP42 / NUPL2 (NUP42) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human NUP42 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Nucleoporin 42 (NUP42), also known as NupL1, is a component of the nuclear pore complex (NPC), which regulates the bidirectional transport of macromolecules such as RNA and proteins between the nucleus and cytoplasm. NUP42 is specifically associated with the cytoplasmic face of the NPC and plays a critical role in mRNA export and other transport pathways. It interacts with the CRM1 export receptor, facilitating the export of certain cargoes during cellular stress responses and viral infections. Mutations or dysregulation of NUP42 can affect nucleocytoplasmic transport, contributing to cellular senescence, developmental defects, and diseases such as cancer and neurodegenerative disorders. Understanding its function provides insights into the dynamics of nuclear-cytoplasmic communication and the mechanisms underlying related pathologies.
Características del producto
category
ELISA Kits
immunogen target
Nucleoporin NUP42 / NUPL2 (NUP42)
reactivity
Human
test range
0.312 ng/ml - 20 ng/ml
sensitivity
< 0.16 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
CG1,NLP1,UIP1,Hcg1,NLP-1,NLP_1,NUPL2,Nucleoporin-like protein 2, nucleoporin-like protein 1
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
NUP42
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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