Human Nucleoporin 153 kDa (NUP153) Protein
Pida mas información
935106861
info@markelab.com
Precio
221€ (10 µg)
Protein NUP153
proveedor
Abbexareference
abx166550Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Nucleoporin 153 kDa Protein is a recombinant Human protein expressed in E. coli.
Background
Nucleoporin 153 (NUP153) is an essential component of the nuclear pore complex (NPC) that plays a significant role in nucleocytoplasmic transport NUP153 is involved in the structural maintenance of the NPC and aids in the selective trafficking of proteins, RNA, and ribosomal subunits across the nuclear envelope It functions as an anchor point for other nucleoporins, stabilizing the nuclear pore structure and facilitating the proper exchange of molecules between the nucleus and cytoplasm NUP153 also participates in the regulation of gene expression, ensuring the efficient export of mRNA from the nucleus to the cytoplasm for translation During cell division, NUP153 helps maintain nuclear envelope integrity, ensuring proper nuclear compartmentalization and cell cycle progression Dysregulation of NUP153 has been linked to various diseases, including cancers and neurodegenerative disorders, where faulty nuclear transport can disrupt cellular processes, leading to genomic instability and abnormal cell proliferation
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Nucleoporin 153kDa (NUP153)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 55.0 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser1238-Lys1468 Tag: N-terminal His tag and GST tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
NUP153
dry ice
No
availability
Shipped within 5-7 working days.
alias
N153,HNUP153,nucleoporin 153kDa,Nuclear pore complex protein Nup153
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
Quizá le pueda interesar
anti- NUP153 antibody
proveedor
FineTestreference
FNab05921Tested Applications
ELISA, WB, IPreactivity
human,mouse,ratstatus
RUOclonality
polyclonalComponent of the nuclear pore complex(NPC), a complex required for the trafficking across the nuclear envelope. Function...
Precio a consultar
Ver másNucleoporin 153 (NUP153) Antibody
proveedor
Abbexareference
abx034230Tested Applications
ELISA, WB, FCMreactivity
Humanstatus
RUOclonality
PolyclonalNuclear pore complexes are extremely elaborate structures that mediate the regulated movement of macromolecules between ...
292.5€ (80 µl)
Ver másNucleoporin 153 kDa (NUP153) Antibody
proveedor
Abbexareference
abx114225Tested Applications
ELISA, WBreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalNucleoporin 153 kDa Antibody is a Rabbit Polyclonal antibody against Nucleoporin 153 kDa.
637€ (100 µl)
Ver más