Human Nucleoporin 153 kDa (NUP153) ELISA Kit
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Description
Human Nucleoporin 153 kDa (NUP153) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Nucleoporin 153 kDa (NUP153) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Nucleoporin 153 kDa (NUP153) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.094 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P49790 |
| Gene ID | 9972 |
| OMIM | 603948 |
| Alias | N153,HNUP153,nucleoporin 153kDa,Nuclear pore complex protein Nup153 |
| Background | Elisa kits for NUP153 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Nucleoporin 153 (NUP153) is an essential component of the nuclear pore complex (NPC) that plays a significant role in nucleocytoplasmic transport NUP153 is involved in the structural maintenance of the NPC and aids in the selective trafficking of proteins, RNA, and ribosomal subunits across the nuclear envelope It functions as an anchor point for other nucleoporins, stabilizing the nuclear pore structure and facilitating the proper exchange of molecules between the nucleus and cytoplasm NUP153 also participates in the regulation of gene expression, ensuring the efficient export of mRNA from the nucleus to the cytoplasm for translation During cell division, NUP153 helps maintain nuclear envelope integrity, ensuring proper nuclear compartmentalization and cell cycle progression Dysregulation of NUP153 has been linked to various diseases, including cancers and neurodegenerative disorders, where faulty nuclear transport can disrupt cellular processes, leading to genomic instability and abnormal cell proliferation
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