Human Nuclear receptor subfamily 6 group A member 1 (NR6A1) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Nuclear receptor subfamily 6 group A member 1 (NR6A1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx535832
tested applications
ELISA
Description
Human Nuclear receptor subfamily 6 group A member 1 (NR6A1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Nuclear receptor subfamily 6 group A member 1 (NR6A1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Nuclear receptor subfamily 6 group A member 1 (NR6A1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q15406 |
| Gene ID | 2649 |
| OMIM | 602778 |
| Alias | RTR,GCNF,NR61,Hrtr,CT150,GCNF1,hGCNF,Germ cell nuclear factor,Retinoid receptor-related testis-specific receptor |
| Background | Elisa kits for NR6A1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Nuclear receptor subfamily 6 group A member 1 (NR6A1), also known as NURR1, is a nuclear receptor that plays a critical role in the development of the central nervous system, particularly in the differentiation and maintenance of dopaminergic neurons NR6A1 is highly expressed in areas of the brain involved in movement, such as the substantia nigra, where it is essential for the proper formation and function of dopaminergic neurons It regulates the expression of genes that control neurogenesis, cell survival, and synaptic plasticity, and its dysfunction has been linked to neurodegenerative diseases, such as Parkinson’s disease NR6A1 also plays a role in regulating immune responses and modulating inflammation, particularly in the context of neuroinflammation, which is often observed in neurodegenerative disorders Mutations or altered expression of NR6A1 can lead to impaired neuronal function, cognitive decline, and motor deficits In addition, NR6A1’s involvement in the regulation of immune responses and its impact on neural differentiation make it a potential therapeutic target for neurodegenerative diseases and inflammatory conditions in the nervous system
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