Human Nuclear Receptor Subfamily 0 Group B Member 1 (NR0B1) ELISA Kit
500.5€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Nuclear Receptor Subfamily 0 Group B Member 1 (NR0B1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx259535
tested applications
ELISA
Description
Human Nuclear Receptor Subfamily 0 Group B Member 1 (NR0B1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DAX-1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Nuclear Receptor Subfamily 0 Group B Member 1 (NR0B1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.094 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P51843 |
| Gene ID | 190 |
| OMIM | 300018 |
| Alias | AHC,AHX,DSS,GTD,HHG,AHCH,DAX1,DAX-1,NROB1,SRXY2,Nuclear receptor DAX-1,DSS-AHC critical region on the X chromosome protein 1 |
| Background | Elisa kits for NR0B1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Nuclear receptor subfamily 0 group B member 1 (NR0B1), also known as DAX-1, is a nuclear receptor that plays a crucial role in the regulation of endocrine function, particularly in the development and function of the gonads and adrenal glands NR0B1 acts as a transcriptional regulator by binding to DNA and influencing the expression of target genes involved in steroidogenesis, sexual differentiation, and reproductive function It functions primarily by repressing the activity of other nuclear receptors, such as steroid hormone receptors, and plays a key role in controlling the balance of sex hormones and their effects on the body NR0B1 is essential for the proper development of the hypothalamic-pituitary-gonadal axis, and mutations in the NR0B1 gene have been associated with disorders such as 46, XY gonadal dysgenesis, a condition that results in underdeveloped gonads and infertility Additionally, NR0B1 is involved in regulating the development of the central nervous system and the regulation of bone metabolism Dysregulation of NR0B1 has been linked to several endocrine disorders and cancers
Related Products
Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1) Antibody
NR0B1 Antibody is a Rabbit Polyclonal antibody against NR0B1. This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq, Jul 2008].
Ver Producto
Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1) Antibody
NR0B1 Antibody is a Rabbit Polyclonal antibody against NR0B1.
Ver Producto
Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1) Antibody
Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1) Antibody is a Rabbit Polyclonal antibody against Nuclear Receptor Subfamily 0, Group B, Member 1 (NR0B1).
Ver Producto