Human Nuclear receptor ROR-gamma (RORC) ELISA Kit
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935106861
info@markelab.com
Precio
493.75€ (96 tests)
Elisa Kits RORC
proveedor
Abbexareference
abx253463Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Nuclear receptor ROR-gamma (RORC) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Nuclear receptor ROR-gamma concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
RAR related orphan receptor C (RORC), also known as RORγ, is a nuclear receptor that plays a crucial role in regulating immune responses, particularly in the differentiation of Th17 cells, which are a subset of helper T cells involved in autoimmune diseases RORC is essential for the regulation of inflammatory processes and the production of pro-inflammatory cytokines, making it a key player in the pathogenesis of conditions like rheumatoid arthritis, psoriasis, and multiple sclerosis RORC also influences the development of the thymus and other immune organs, playing a role in maintaining immune homeostasis It is involved in the regulation of metabolic processes and the response to oxidative stress and environmental factors Dysregulation of RORC expression is linked to autoimmune diseases, chronic inflammation, and cancer, where altered immune regulation contributes to disease progression Targeting RORC with specific inhibitors has been explored as a therapeutic strategy to manage autoimmune diseases and inflammatory conditions, highlighting its potential as a drug target in immune-related therapies
Características del producto
category
ELISA Kits
immunogen target
Nuclear receptor ROR-gamma (RORC)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay type
Competitive
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
TOR,RORG,RZRG,IMD42,NR1F, RZR-GAMMA,Nuclear receptor ROR-gamma,RAR-related orphan receptor C,Nuclear receptor subfamily 1 group F member 3
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
RORC
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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