Human NR1H4(Bile acid receptor) ELISA Kit
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human NR1H4(Bile acid receptor) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH2066
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.156-10ng/ml |
| Size 1 | 96T |
| Sample Type | Serum,Plasma,Tissue homogenates,Other biological fluids |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 6 months |
| UniProt ID | Q96RI1 |
| Alias | BAR,FXR,HRR1,HRR-1,PFIC5,RIP14,Bile acid receptor,Farnesoid X-activated receptor,Nuclear receptor subfamily 1 group H member 4 |
| Background | Elisa Kits NR1H4 |
| Status | RUO |
Nuclear receptor subfamily 1 group H member 4 (NR1H4), also known as FXR (farnesoid X receptor), is a nuclear receptor that plays a crucial role in regulating bile acid metabolism, liver function, and glucose homeostasis NR1H4 is expressed primarily in the liver, intestine, and kidneys, where it regulates the synthesis, transport, and catabolism of bile acids, which are essential for digestion and the absorption of fats FXR also influences lipid and glucose metabolism, helping maintain energy balance and insulin sensitivity in the liver and other metabolic tissues It plays a key role in protecting the liver from bile acid toxicity by regulating the expression of genes involved in bile acid homeostasis Dysregulation of FXR signaling has been associated with liver diseases such as non-alcoholic fatty liver disease (NAFLD), cirrhosis, and cholestasis, as well as metabolic diseases like obesity and diabetes FXR has emerged as a therapeutic target for managing liver diseases, metabolic syndrome, and conditions related to bile acid imbalances, making it an important receptor for drug development in these areas
Related Products
Human NR1H4(Bile acid receptor) ELISA Kit
Ver Producto
Bile Acid Receptor (NR1H4) Antibody
NR1H4 Antibody is a Rabbit Polyclonal Antibody against NR1H4.
Ver Producto
Human Bile Acid Receptor (NR1H4) ELISA Kit
Human Bile Acid Receptor (NR1H4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Bile Acid Receptor (NR1H4) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Farnesoid X Receptor (FXR)
Ver Producto