Human Neuropeptide Y Receptor Y1 (NPY1R) ELISA Kit
715€ (96 tests)
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name
Human Neuropeptide Y Receptor Y1 (NPY1R) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx152550
tested applications
ELISA
Description
Human Neuropeptide Y Receptor Y1 (NPY1R) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Neuropeptide Y Receptor Y1 (NPY1R) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of NPY1R
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Neuropeptide Y Receptor Y1 (NPY1R) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.13 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P25929 |
| Gene ID | 4886 |
| OMIM | 162641 |
| Alias | NPY1R,NPY1-R,NPYR,NPY-Y1 receptor,FC5,neuropeptide Y receptor type 1,Y1-R |
| Background | Elisa kits for NPY1R |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
NPY1R is a G protein-coupled receptor activated by neuropeptide Y (NPY), peptide YY (PYY), and pancreatic polypeptide (PP). It is predominantly expressed in the central nervous system (CNS), particularly in the hypothalamus, as well as peripheral tissues, where it regulates appetite, energy homeostasis, and cardiovascular function. NPY1R couples to Gi/o proteins, inhibiting adenylate cyclase, reducing cAMP levels, and modulating calcium and potassium channels. Activation of NPY1R stimulates feeding behavior and reduces energy expenditure, contributing to weight gain and energy conservation. NPY1R is also involved in regulating stress responses, anxiety, and blood pressure. Dysregulation of NPY1R signaling is linked to obesity, metabolic disorders, and cardiovascular dysfunction. NPY1R antagonists are being explored as potential therapeutics for obesity and metabolic syndrome, as blocking NPY1R can reduce food intake and promote weight loss. Additionally, NPY1R modulators are being investigated for anxiety and stress-related conditions due to its role in emotional regulation.
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